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Leukemia is a heterogeneous clonal disorder characterized by defects in cell differentiation and the death of hematopoietic progenitor cells. Despite major advances in drug development, leukemia treatment remains limited by resistance to chemotherapeutic agents in many patients [ 12 ]. Thus, there remains a need for new therapeutic agents and strategies to improving the leukemia cure rate.
The Achilles heel of anticancer treatments is intrinsic or acquired resistance. Among many targeted therapies, the DNA repair inhibitors show limited efficacy due to rapid emergence of resistance. Transcriptomes of cell populations recovering from cyclic treatments or mock treatment were compared.
Sign in. Not Rated min Drama, Romance, Thriller. A woman is hired as a handmaiden to a Japanese heiress, but secretly she is involved in a plot to defraud her.
The figure, specifically the nude, is arguably the most widely used subject matter in the history of art. From the Venus of Willendorf and Ancient Greece to Picasso and Giacometti, the nude figure has been used formally and conceptually to represent not only the model, but the emotions and ideals of their times and places. In this global world, what does it mean to use the nude in our modern age, particularly with the advent of new materials and technologies, both in the creation and spread of the artwork.
Or sign in with one of these services. If you've just finished watching Korean dramas on Netflix, then check out this list of new and popular Korean variety shows, which features talk shows, cooking shows, and reality programs. Sung Si-kyung's kissing scene with a Japanese actress was the highlight of the music video.
Ahn Mo-rae and Han Sang-in have been friends since childhood. He didn't mind that she followed him around, calling him hyeong or Big Brother though Korean girls are supposed to call older guys oppaand their marital relationship is an odd but appealing mix of hot sex and best buddies. The day of their wedding anniversary is pretty eventful.